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At the 8 mg/day dose, "hydromethylthione reduced the rate of clinical decline and brain atrophy by almost half in patients with adequate blood levels of the drug compared to the patients who had minimal blood levels of the drug at the same dose," study investigator Claude Wischik, MD, PhD, who is also executive chairman of TauRx Therapeutics and professor of psychiatric gerontology at the University of Aberdeen, United Kingdom, told Medscape Medical News.