from scrapy.crawler import CrawlerRunner
from scrapy.utils.project import get_project_settings
...
...
settings = get_project_settings()
runner = CrawlerRunner(settings)
runner.crawl(MySpider)  # run MySpider
runner.stop()  # kill all jobs

#EbaySearcher.py
imports...

class MySpider(CrawlSpider):
    name = "ebay"
    #coooode

def run_crawler():
    global runner
    settings = get_project_settings()
    runner = CrawlerRunner(settings)
    runner.crawl(MySpider)

def stop_crawler():
    runner.stop()




#back.py

imports and inits... and cooode...
class MainPage(tk.Frame):
    
    def __init__(self,parent,controller):
        tk.Frame.__init__(self,parent)

        self.config(bg='#53a0b2')
        
        label = ttk.Label(self,text='Выбери действие', background='#53a0b2',foreground='white', font = LARGE_FONT)
        label.pack()
        self.entry_search = ttk.Entry(self)
        self.entry_search.delete(0,'end')
        self.entry_search.insert(0,'iphone black 7')
        self.entry_search.pack()

        self.btnsearch = tk.Button(self, text='Search',relief='flat')
        self.btnsearch.bind('<Button-1>',lambda event: self.search())
        self.btnsearch.pack()
    
    def search(self):
        self.btnsearch['text']='Stop'
        self.btnsearch.bind('<Button-1>',lambda event: self.stop())
        run_crawler()

    def stop(self):
        self.btnsearch['text']='Search'
        self.btnsearch.bind('<Button-1>',lambda event: self.search())
        stop_crawler()

app = SeaofBTCapp()
app.mainloop()