Battlefield 2 uses Python for all of its add-ons and a lot of its functionality.[1]
Bridge Commander[2]
Civilization IV uses Python for most of its tasks
Disney's Toontown Online is written in Python and uses Panda3D for graphics.
Doki Doki Literature Club!, a psychological horror visual novel using the Ren'Py engine
Eve Online uses Stackless Python.
Freedom Force[citation needed]
Frets on Fire is written in Python and uses Pygame
Mount & Blade is written in Python.
Pirates of the Caribbean Online is written in Python and uses Panda3D for graphics.
The Sims 4 uses Python[3]
The Temple of Elemental Evil, a computer role-playing game based on the classic Greyhawk Dungeons & Dragons campaign setting
Unity of Command (video game) is an operational-level wargame about the 1942/43 Stalingrad Campaign on the Eastern Front.
Vampire: The Masquerade – Bloodlines, a computer role-playing game based on the World of Darkness campaign setting[4]
Vega Strike, an open source space simulator, uses Python for internal scripting
World of Tanks uses Python for most of its tasks